Antifungal activities of amino acid ester functional pyrazolyl compounds against Fusarium oxysporum f.sp. albedinis and Saccharomyces cerevisiae yeast

Abstract

Series of functional multidendate ligands based on pyrazole and amino acid derivatives were prepared in good and excellent yields (75-85%) by condensation of one equivalent of amino acid ester hydrochloride substrates with two equivalents of (3,5- dimethyl-1H–pyrazol-1-yl)methanol. These tridentate functionalized compounds and their starting materials were screened for their antifungal activities against Fusarium oxysporum f.sp. albedinis and the yeast of Saccharomyces cerevisiae. Considerable activities were recorded with respect to the two studied microorganisms.